Despite the challenges making headlines throughout 2025, Good News of the Week hit your inbox every Friday morning, offering a fresh dose of positivity as you turned the page on yet another week. As we share this year’s top stories in Good News of the Year, we hope you will enjoy this positive look back at 2025, and we look forward to creating and curating more good news with you in 2026.
See what San Diego accomplished in Good News of the Year:
New neighbors and local upgrades
As San Diego became home for many notable companies, reflecting our global reputation in life sciences, tech, and tourism, we also cut the ribbon on highly-anticipated upgrades to the region. Some highlights:
- TED to move flagship conference to San Diego beginning in 2027, with support from EDC, Tourism Authority, Convention Center
- SAN opens Terminal 1, welcomes first passengers
- Alexandria Real Estate Equities, Inc. secures Novartis as megacampus tenant
- French medtech company Germitec locates North American HQ in San Diego
- Chula Vista’s Gaylord Pacific Resort and Convention Center opens to the public
- Southwest expands services to Maui, Spokane, more
- GKN Aerospace unveils $55M repair facility in El Cajon
- Saronic Technologies opens new 80K-square-foot facility in Downtown
- Cross Border Xpress announces $100M expansion
Here’s the deal
San Diego continued to bring in the deals, partnerships, and acquisitions that forged meaningful collaboration—a testament to both the people who live and work here, as well as growing appetites for our innovative companies, programs, and ideas. Among this year’s high-impact partnerships, these topped our list:
- Novartis acquires Avidity Biosciences for $12B, Regulus for up to $1.7B
- Eli Lilly, Rznomics announce $1.3B partnership targeting hearing loss
- Blackstone, TPG Capital to acquire San Diego’s Hologic for $18.3B
- Neomorph, AbbVie announce $1.6B partnership to develop molecular glue degraders
- BioMed Realty secures Pfizer’s San Diego campus in $255M deal
- Rady Children’s Hospital, Children’s Hospital of Orange County celebrate merger
- Price Philanthropies, Prebys Foundation, San Diego Foundation partner on $70M housing, food, healthcare fund
- San Diego compliance startup Drata acquires SafeBase for $250M
A sunny startup incubator
Ranked as a top city for innovation, San Diego’s high profile reflects our region’s diverse skillset and expertise. This year’s top venture funds and IPOs showed continued demand for homegrown tech, life sciences, cybersecurity, and defense technologies:
- Carlsbad-based spine surgery medtech Carlsmed files $100M IPO
- San Diego defense tech startup Shield AI raises $240M, reaches $5.3B valuation
- Crystalys Therapeutics launches with $205M to alleviate gout pain
- Aardvark Therapeutics raises $94.2M IPO
- Timberlyne Therapeutics launches with $180M Series A to advance autoimmune disorder and cancer treatments
- Wearable biosensor startup Biolinq closes $100M Series C
- Cybereason raises $120M for cyber attack protection
From classrooms to careers
San Diego’s education systems remained strong, focusing on continued innovation and increasing access between two-year and four-year institutions, as well as industry. See our region’s resilience in education:
- SDSU earns R1 classification, begins construction on Mission Valley Innovation District, partners with San Diego Community College District to expand higher education access
- UCSD, General Atomics launch Fusion Data Science and Digital Engineering Center
- PLNU, EDC launch biotech pathway scholarship program supporting community college students
- USD, Mexico’s CETYS Universidad celebrate inaugural binational graduates
- National University, MiraCosta College partner on discounted higher education opportunities
- CSUSM launches historic $200M Blueprint for the Future campaign, announces bachelor’s degree programs at Southwestern College
Life-changing and life-saving
San Diego companies remained at the forefront of innovation, making breakthroughs in cancer therapies, medical testing, and AI integration—and advancing our region’s competitiveness on a global scale. Key milestones included:
- Qualcomm’s Snapdragon Ride Pilot debuts on new BMW iX3 SUVs
- Curebound’s Concert for Cures, Elton John raise record $11.5M for regional cancer research
- Solar Turbines emerges as leader in AI-powered turbine development
- Dexcom’s G7 15-day continuous glucose monitor secures FDA approval
- Illumina expands access to oncology tests with Medicare coverage
- Vertex Pharmaceuticals’ non-opioid pain medication earns FDA approval
- Scripps Research, Viome develop first at-home colon cancer test
San Diego on a global stage
In 2025, San Diego continued creating the products, research, and ideas that make a global impact across all time zones. We dare you to find a place San Diego innovation hasn’t touched; see our region’s reach for yourself:
- General Atomics completes novel fusion energy magnet for ITER project in France
- SAN debuts nonstop flights to Panama City via Copa Airlines, Amsterdam
- UC San Diego, ITJ partner on binational innovation hub in Tijuana
- YMCA of San Diego County, Mexico sign cross-border resource-sharing agreement
- Carlsbad’s Ionis strikes $940M deal with Japan’s Ono Pharmaceutical
- Kumquat Bio inks $1.3B deal with Germany-based Bayer
- San Diego’s LENZ Therapeutics, Lotus announce $125M Asia distribution partnership
- Vuori opens first South Korean store in Seoul, largest in Asia
Military legacy, innovation future
Contributing an estimated $61.3 billion in annual regional economic impact, San Diego’s military presence in 2025 reinforced what we know is true: The cluster fuels not only our economy, but defense innovation on a larger scale.
- General Dynamics NASSCO wins $200M Navy contract, secures $72.6M DOD submarine tender contract
- Viasat lands $4.8B NASA satellite communications, government data encryption, DOD autonomous vehicle contracts
- BAE Systems’ San Diego shipyard earns $64M Navy repair contract
- ESET North America recruited by US government to disrupt international malware cyberattacks
- Northrop Grumman secures $39.7M Navy signal jammer contract
- Cubic Corporation lands eight-year Army contract
- Austal USA secures $10.7M Navy contract
- MetroConnect VII alum GALT Aerospace secures $145M Marine Corps contract
- Firestorm grows operations with $47M Series A, secures $100M Air Force contract
A clean, green San Diego
Named among eight A-rated cities in the US for climate action, San Diego’s companies and organizations remained uniquely positioned to drive green decision-making and inspire collaboration locally and across the border. The region’s impact:
- Port of San Diego invests $277M, reaches 80 percent of clean air goals
- San Diego Community Power, Calpine Community Energy, San Diego Foundation award $900K for regional clean energy projects
- Republic Services eases commercial venue composting with new Thor machine, partners with San Diego Padres for state-of-the-art composting program
- SANDAG launches zero-emission transportation program in Southeast San Diego
- San Diego Foundation awards $650K in binational grants for Tijuana River projects
- Chula Vista approves 50-megawatt battery storage project for clean energy reliability
Let’s go, San Diego!
The chants we heard from the crowd at Snapdragon Stadium as we welcomed our region’s MLS team created a refreshed wave of pride, resulting in a season of wins that transcended languages and touched hearts across our binational region. See what we rooted for:
- San Diego FC reaches Western Conference Final, sets MLS records in its inaugural season
- San Diego Wave FC lands NWSL playoff spot for third time, retires Alex Morgan jersey
- Padres earn playoff spot for the fourth time in six seasons
- SeaWorld San Diego celebrates reopening of updated Journey to Atlantis coaster
- Barnes Tennis Center hosts USA Pickleball National Championships
- Chula Vista’s Jessica Sanchez wins “America’s Got Talent” Season 20
- NASCAR announces Naval Base Coronado street race in 2026
Our good news
This year, EDC celebrated our 60th anniversary of building an inclusive economy and driving forward our region’s most impactful industries, talent, and employers with and through you. Our favorite EDC moments:
- EDC celebrates 60th anniversary, welcomes Padres’ Tom Seidler as board chair
- EDC publishes annual Inclusive Growth progress update revealing that fundamental challenges remain
- EDC’s Economic Development team, Research Bureau publish statewide study on fusion’s economic impact and roadmap to commercialization
- World Trade Center San Diego (WTCSD) leads France trade mission with Rep. Peters, Mayor Gloria
- WTCSD, EDC’s Research Bureau analyze Cali Baja’s trade growth and competitiveness that fuels 95K local jobs in strategic sectors
- Advancing San Diego places 210 interns across 110 companies, covering $1.38M in payroll
- WTCSD helps 15 MetroConnect companies grow combined exports by $10.1M
- WTCSD supports SAN in securing Panama and Amsterdam as two new international nonstop destinations
- EDC hosts inaugural San Diego Business Impact Awards together with JPMorganChase
- Advancing San Diego publishes 12th talent demand report exploring local healthcare needs